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Volume 6
Main Index

Issue 1


Steroidal Heterocycles. VII.1 Androstano[2,3-d]isoxazoles and Related Compounds
A. J. Manson, F. W. Stonner, H. C. Neumann, R. G. Christiansen, Robert L. Clarke, J. H. Ackerman, D. F. Page, J. W. Dean, D. K. Phillips, G. O. Potts, A. Arnold, A. L. Beyler, and R. O. Clinton
pp 1 - 9; DOI:
10.1021/jm00337a001
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Citrulline-Containing Analogs of Bradykinin
Miguel A. Ondetti
pp 10 - 16; DOI:
10.1021/jm00337a002
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Metal Complexation of the Tetracycline Hydrochlorides
James T. Doluisio and Alfred N. Martin
pp 16 - 20; DOI:
10.1021/jm00337a003
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The Binding of Tetracycline Analogs to Conalbumin in the Absence and Presence of Cupric Ions
James T. Doluisio and Alfred N. Martin
pp 20 - 23; DOI:
10.1021/jm00337a004
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Synthesis of Derivatives of Isophthalamic Acid as X-Ray Contrast Agents
G. Brooke Hoey, Robert D. Rands, George DeLaMater, Douglas W. Chapman, and Philip E. Wiegert
pp 24 - 26; DOI:
10.1021/jm00337a005
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The Synthesis of Arylalkylaminopropionamide Analogs of Lysergic Acid Diethylamide and their Effect upon Isolated Cholinesterase Systems. II
Andrew Lasslo, Pauline D. Waller, and Glenda J. Epperson
pp 26 - 28; DOI:
10.1021/jm00337a006
PDF
Bicyclic Homologs of Piperazine. Synthesis of Pharmacologically Active 8-Methyl-3,8-diazabicyclo[3.2.1]octanes. III.
Giorgio Cignarella, Emilio Occelli, Giulio Maffii, and Emilio Testa
pp 29 - 36; DOI:
10.1021/jm00337a007
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The Synthesis and Antineoplastic Properties of Selenoguanine, Selenocytosine and Related Compounds
Henry G. Mautner, Shih-Hsi Chu, Julian J. Jaffe, and Alan C. Sartorelli
pp 36 - 39; DOI:
10.1021/jm00337a008
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Trifluoromethyl Compounds Related to Nucleic Acid Bases
John A. Barone
pp 39 - 42; DOI:
10.1021/jm00337a009
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Potential Anticancer Agents.1 LXXIX. Aromatic Nitrogen Mustards Derived from Cysteine2
Robert H. Iwamoto, Edward M. Acton, Leonard O. Ross, W. A. Skinner, B. R. Baker, and Leon Goodman
pp 43 - 46; DOI:
10.1021/jm00337a010
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Synthesis of Hexahydroazepinyl-bis(aziridinyl)phosphine Oxide, Sulfide, and Related Compounds for Cancer Therapy
K. C. Tsou and Karl Hoegerle
pp 47 - 49; DOI:
10.1021/jm00337a011
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Synthesis of N-Phosphorylated Derivatives of Nitrogen Mustards with Latent Cytotoxicity
Orrie M. Friedman, Eliahu Boger, Vytautas Grubliauskas, and Harold Sommer
pp 50 - 58; DOI:
10.1021/jm00337a012
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2-Amino-5-pyrimidinesulfonamides
William T. Caldwell, Walter Fiddler, and Norman J. Santora
pp 58 - 59; DOI:
10.1021/jm00337a013
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Further Studies on N-Arylsulfonyl-N′-alkylureas
Frederick J. Marshall, Max V. Sigal, Hugh R. Sullivan, Charlene Cesnik, and Mary A. Root
pp 60 - 63; DOI:
10.1021/jm00337a014
PDF
Monoamine Oxidase Inhibitors. The Synthesis and Evaluation of a Series of Substituted Alkylhydrazines
D. J. Drain, J. G. B. Howes, R. Lazare, Ann M. Salaman, R. Shadbolt, and H. W. R. Williams
pp 63 - 69; DOI:
10.1021/jm00337a015
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The Synthesis of Cycloheptatriene Homologs of Some Physiologically Active Compounds
Kenneth Conrow and Dhirubhai Naranji Naik
pp 69 - 72; DOI:
10.1021/jm00337a016
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N-Pantoyl-(substituted-phenyl)alkylamines, Inhibitory Analogs of Pantothenic Acid
Edwin D. Parker, Thomas J. Cogdell, Jean S. Humphreys, Charles G. Skinner, and William Shive
pp 73 - 76; DOI:
10.1021/jm00337a017
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Conformational Aspects of Drug Action. I. The Effects of D(-)Pseudoephedrine on the Action of Certain Pressor Amines
Jules B. LaPidus, Arthur Tye, Popat Patil, and Balkrishna A. Modi
pp 76 - 77; DOI:
10.1021/jm00337a018
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A Hydroxamic Acid Analog of Cortisone
R. W. Kierstead, A. Faraone, and M. W. Goldberg
pp 77 - 79; DOI:
10.1021/jm00337a019
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Steroids and Related Products. XVIII.1 The Synthesis of 11β,12α-Dibromoprogesterone2
J. Capitaine, R. Deghenghi, and Ch. R. Engel
pp 79 - 82; DOI:
10.1021/jm00337a020
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Potential Carcinolytic Agents Related to Cyclophosphamide
Orrie M. Friedman, Zinon B. Papanastassiou, Robert S. Levi, Harris R. Till, and Wilson M. Whaley
pp 82 - 83; DOI:
10.1021/jm00337a021
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Synthesis of Potential Antineoplastic Agents. IX. Some Cycloalkyl Mustards and Related Compounds1-3
Frank D. Popp, Sandra Roth, and John Kirby
pp 83 - 85; DOI:
10.1021/jm00337a022
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Potential Anticancer Agents.1 LXXX. Alkylating Agents Related to Phenylalanine Mustard.2 VI. Enantiomeric meta-Phenylalanine Mustards
Helen F. Gram, Bernard J. Berridge, Edward M. Acton, and Leon Goodman
pp 85 - 87; DOI:
10.1021/jm00337a023
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Pyrimidines. III. Some 6-Substituted Di- and Trichloropyrimidines
Herman Gershon, Richard Braun, and Alfred Scala
pp 87 - 89; DOI:
10.1021/jm00337a024
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Antiamebic Agents. VI.1 Analogs of Bialamicol and Related Quinolinols
J. H. Burckhalter, Robert I. Leib, Yun Sung Chough, and Raymond F. Tietz
pp 89 - 90; DOI:
10.1021/jm00337a025
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Issue 2


Studies in the Synthesis and Pharmacology of Aporphines
Jerry A. Weisbach, Cynthia Burns, Edward Macko, and Bryce Douglas
pp 91 - 97; DOI:
10.1021/jm00338a001
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Reserpine Analogs; Phenethylamine Derivatives
A. Lindner, V. Claassen, Th. W. J. Hendriksen, and T. Kralt
pp 97 - 101; DOI:
10.1021/jm00338a002
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Potent Decarboxylase Inhibitors. Analogs of Methyldopa
M. Sletzinger, J. M. Chemerda, and F. W. Bollinger
pp 101 - 103; DOI:
10.1021/jm00338a003
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Structure-Action Relations in N,N-Dimethyl-2-halogenophenethylamines
J. D. P. Graham and M. A. Karrar
pp 103 - 107; DOI:
10.1021/jm00338a004
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Quaternary Ammonium Compounds. III. Antiacetylcholinesterase Activity and Charge Distribution in Aromatic Quaternary Ammonium Compounds
J. Thomas and W. Marlow
pp 107 - 111; DOI:
10.1021/jm00338a005
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The Synthesis and Antitussive Properties of Some Cyclopentane Derivatives
G. P. Ellis, L. Golberg, J. King, and P. Sheard
pp 111 - 117; DOI:
10.1021/jm00338a006
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Piperidino Groups in Antitussive Activity
Yoshitoshi Kasé, Tomokazu Yuizono, and Mieko Muto
pp 118 - 122; DOI:
10.1021/jm00338a007
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Antihypertensive Agents. I. Non-diuretic 2H-1,2,4-Benzothiadiazine 1,1-Dioxides
John G. Topliss, Margaret H. Sherlock, Hans Reimann, Leroy M. Konzelman, Elizabeth P. Shapiro, Berit W. Pettersen, Helen Schneider, and Nathan Sperber
pp 122 - 127; DOI:
10.1021/jm00338a008
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Synthetic Analgesics. IV. Synthesis of Enantiomers of Basic Anilides Containing the Phenalkyl Moiety
W. B. Wright and R. A. Hardy
pp 128 - 130; DOI:
10.1021/jm00338a009
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New Psychotropic Agents.1a IV. Derivatives of Dibenzo[a,d][1,4]cycloöctadiene
Stanley O. Winthrop, M. A. Davis, F. Herr, J. Stewart, and Roger Gaudry
pp 130 - 132; DOI:
10.1021/jm00338a010
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New Sedative and Hypotensive Phenylpiperazine Esters and Carbamates
Shin Hayao, R. N. Schut, and W. G. Strycker
pp 133 - 135; DOI:
10.1021/jm00338a011
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Substituted 3-Thiomorpholinones
H. Lehr, S. Karlan, and M. W. Goldberg
pp 136 - 141; DOI:
10.1021/jm00338a012
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The Chemistry of the Benzylpyridines. V. β-Phenyl-β-pyridyl-β-hydroxypropionic Acids and Derivatives as Antispasmodic Agents
Frank J. Villani, Mary S. King, and Florence J. Villani
pp 142 - 144; DOI:
10.1021/jm00338a013
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Sequential Blockage as a Theoretical Basis for Drug Synergism
Martin L. Black
pp 145 - 153; DOI:
10.1021/jm00338a014
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Monoamine Oxidase Inhibitors. IV. Some Dialkylaminophenylalkylhydrazines and Related Compounds
Jacob Finkelstein, John A. Romano, Elliot Chiang, and John Lee
pp 153 - 155; DOI:
10.1021/jm00338a015
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Steroids. CCV.1 Ring A Modified Hormone Analogs. Part I. Some Ring A Olefins
A. Bowers, A. D. Cross, J. A. Edwards, H. Carpio, M. C. Calzada, and E. Denot
pp 156 - 161; DOI:
10.1021/jm00338a016
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Steroids. CCVI.1 Ring A Modified Hormone Analogs. Part II. 2-Methylene Androstanes and 2-Methyl-Δ1, Δ2 and Δ3-Androstenes2
A. D. Cross, J. A. Edwards, J. C. Orr, B. Berköz, L. Cervantes, M. C. Calzada, and A. Bowers
pp 162 - 166; DOI:
10.1021/jm00338a017
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Steroids. CCVII. Ring A Modified Hormone Analogs. Part III.1 2-Formyl-Δ2-androstenes and Related Compounds. A New Class of Potent Anabolic Agents2
J. C. Orr, O. Halpern, P. G. Holton, F. Alvarez, I. Delfin, A. De La Roz, A. M. Ruiz, and A. Bowers
pp 166 - 173; DOI:
10.1021/jm00338a018
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Steroids. CCVIII.1 Ring A Modified Hormone Analogs. Part IV. 2-Chloro and 2-Halomethyl-Δ2-androstenes
J. A. Edwards, P. G. Holton, J. C. Orr, L. C. Ibanez, E. Necoechea, A. De La Roz, E. Segovia, R. Urquiza, and A. Bowers
pp 174 - 177; DOI:
10.1021/jm00338a019
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Steroids. CCIX.1 Ring A Modified Hormone Analogs. Part V. 2-Methylene-3-oxygenated Androstanes
J. A. Edwards, M. C. Calzada, and A. Bowers
pp 178 - 182; DOI:
10.1021/jm00338a020
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Steroids. CCX.1 Ring A Modified Hormone Analogs. Part VI. Δ2- and 2-Formyl-Δ2-17β-ol-17α-propionic Acid Spirolactones
Pierre Crabbé, J. Revilla, and A. Bowers
pp 182 - 184; DOI:
10.1021/jm00338a021
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A Systematic Investigation of Thioxanthen-9-ones and Analogs as Potential Antitumor Agents
Erwin J. Blanz and Frederic A. French
pp 185 - 191; DOI:
10.1021/jm00338a022
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Anaphylactic Microshock in the Screening of Some Theophyllines and Benzylphenoxyaminoalkanes for Antiasthmatic Activity
Wolfgang Richter, Kurt Rubinstein, and Niels Elming
pp 192 - 194; DOI:
10.1021/jm00338a023
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Steroids. CLXXXIII.1 New Anabolic Agents from Steroids2
John A. Zderic, H. Carpio, A. Ruiz, D. Chávez Limón, F. Kincl, and H. J. Ringold
pp 195 - 198; DOI:
10.1021/jm00338a024
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Steroids. CCXIII.1 Synthesis of Some 6-Chlorotestosterone Derivatives
A. D. Cross, H. Carpio, and H. J. Ringold
pp 198 - 200; DOI:
10.1021/jm00338a025
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Hydroxyurea. A New Type of Potential Antitumor Agent
Barbara Stearns, Kathryn A. Losee, and Jack Bernstein
pp 201 - 201; DOI:
10.1021/jm00338a026
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N-(3-Phthalidyl)-tetracycline, a New Carboxamido Derivative of Tetracycline
Edmund S. Granatek, Murray A. Kaplan, and Frank H. Buckwalter
pp 202 - 202; DOI:
10.1021/jm00338a027
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Compounds Related to Carnitine: Derivatives of 4-Dimethylamino-3-hydroxybutyric Acid
F. Keller, R. R. Engle, and M. W. Klohs
pp 202 - 203; DOI:
10.1021/jm00338a028
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Synthesis of Isothiocyanates as Potential Antineoplastic Agents
J. H. Burckhalter and Dilbagh S. Bariana
pp 203 - 205; DOI:
10.1021/jm00338a029
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Nuclear Substituted 2-Amino-1-(2-pyridyl)propanes
Alfred Burger and Helen Hu Ong
pp 205 - 207; DOI:
10.1021/jm00338a030
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The Synthesis of S35-(1,2-Dichlorovinyl)-L-Cysteine
R. F. Derr and M. O. Schultze
pp 207 - 208; DOI:
10.1021/jm00338a031
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N-(γ-L-Glutamyl)aminobenzoic Acids
Donald L. Ross, Charles G. Skinner, and William Shive
pp 208 - 210; DOI:
10.1021/jm00338a032
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Agents Affecting Lipid Metabolism. II. Analogs of Mevalonic Acid
Leslie G. Humber, Michael Kraml, Jean Dubuc, and Roger Gaudry
pp 210 - 212; DOI:
10.1021/jm00338a033
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Substituted 3-Phenyl-1,3-benzoxazine-2,4-diones and their Bacteriostatic Activity
Raymond E. Stenseth, Joseph W. Baker, and Daniel P. Roman
pp 212 - 213; DOI:
10.1021/jm00338a034
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4,6-Diamino-1-alkyl-1,2-dihydro-s-triazines
Joseph G. Lombardino
pp 213 - 214; DOI:
10.1021/jm00338a035
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Synthesis of Substituted 2-Phenyl-1,4-benzothiazin-3(4H)-ones and their Activity as Inhibitors of 1,4-Dipyrrolidino-2-butyne
John Krapcho, Attila Szabo, and June Williams
pp 214 - 216; DOI:
10.1021/jm00338a036
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Antiviral Activity of 2,2-Dichloro-4′-formylacetanilide Thiosemicarbazone
R. Stuart Tipson
pp 216 - 217; DOI:
10.1021/jm00338a037
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[4-(Aminoalkylamino)-1-naphthylazo]heterocyclic Compounds, a Novel Class of Schistosomicides
Edward F. Elslager, David B. Capps, Leslie M. Werbel, Donald F. Worth, Jack E. Meisenhelder, Haig Najarian, and Paul E. Thompson
pp 217 - 219; DOI:
10.1021/jm00338a038
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2′-(3-Dimethylaminopropylthio)cinnamanilide and Related Compounds: A New Class of Potent and Relatively Specific Serotonin Inhibitors
John Krapcho, Bernard Rubin, Anne M. Drungis, Ervin R. Spitzmiller, Chester F. Turk, June Williams, Bradford N. Craver, and Josef Fried
pp 219 - 219; DOI:
10.1021/jm00338a039
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Book Reviews

pp 220 - 220; DOI:
10.1021/jm00338a040
PDF

Issue 3


Cyclopropyl and Cyclobutyl Analogs of Phenyl-Substituted Medicinal Agents
Alfred Burger, Robert T. Standridge, and E. J. Ariens
pp 221 - 227; DOI:
10.1021/jm00339a001
PDF
Synthesis of Phenethylamines Related to Mescaline as Possible Psychotomimetic Agents
Orrie M. Friedman, K. N. Parameswaran, and Sumner Burstein
pp 227 - 229; DOI:
10.1021/jm00339a002
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Physiologically Active Compounds. V.1a,b Aminothiol Esters of Substituted Acetic, Chloroacetic, Benzilic, and Related Acids2
C. A. Buehler, Hilton A. Smith, Allen C. Kryger, Roy L. Wells, and Shelby F. Thames
pp 230 - 233; DOI:
10.1021/jm00339a003
PDF
Derivatives of (-)-trans-2,3-Epoxysuccinic Acid and Some of their Biological Effects
Max W. Miller
pp 233 - 237; DOI:
10.1021/jm00339a004
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Some Aspects of the Fate and Relationship of the N-Methyl Group of Morphine to its Pharmacological Activity
Christian Elison, Henry W. Elliott, Melvin Look, and Henry Rapoport
pp 237 - 246; DOI:
10.1021/jm00339a005
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Synthesis of Metabolic Products of Benzoxazoles
James N. Plampin and Cornelius K. Cain
pp 247 - 248; DOI:
10.1021/jm00339a006
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Thio Derivatives of 2,3-Dihydro-4H-1,3-benzoxazin-4-one. Synthesis and Pharmacological Properties
U. M. Teotino, L. Polo Friz, A. Gandini, and D. Della Bella
pp 248 - 250; DOI:
10.1021/jm00339a007
PDF
New Psychotropic Agents. V. Derivatives of 5-Cyano- and 5-Carboxamidodibenzo[a,d]cycloheptadiene
M. A. Davis, Stanley O. Winthrop, J. Stewart, F. A. Sunahara, and F. Herr
pp 251 - 255; DOI:
10.1021/jm00339a008
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Some Analogs of Imipramine
A. M. Monro, R. M. Quinton, and T. I. Wrigley
pp 255 - 261; DOI:
10.1021/jm00339a009
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Quinazolines and 1,4-Benzodiazepines. X.1 Nitro-Substituted 5-Phenyl-1,4-benzodiazepine Derivatives2
L. H. Sternbach, R. Ian Fryer, O. Keller, W. Metlesics, G. Sach, and N. Steiger
pp 261 - 265; DOI:
10.1021/jm00339a010
PDF
2-amino-5-Aryl-2-oxazolines. Potent New Anorectic Agents
George I. Poos, John R. Carson, Janet D. Rosenau, Adolph P. Roszkowski, Nancy M. Kelley, and Janet McGowin
pp 266 - 272; DOI:
10.1021/jm00339a011
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Hypotensive 1,2,4-Benzothiadiazines
Barbara Ann Bierbaum, John J. Traverso, and Calvert W. Whitehead
pp 272 - 275; DOI:
10.1021/jm00339a012
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Sympathetic Nervous System Blocking Agents. Derivatives of Guanidine and Related Compounds
James H. Short, Ursula Biermacher, Daniel A. Dunnigan, and Thomas D. Leth
pp 275 - 283; DOI:
10.1021/jm00339a013
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Studies on Methylglyoxal Bis(guanylhydrazone)1 Analogs. I. Homologs of Methylglyoxal Bis(guanylhydrazone)2
Eugene G. Podrebarac, Wayne H. Nyberg, Frederic A. French, and C. C. Cheng
pp 283 - 288; DOI:
10.1021/jm00339a014
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Carbamates Derived from Aminopurines
Elizabeth Dyer, John M. Reitz, and Russell E. Farris
pp 289 - 291; DOI:
10.1021/jm00339a015
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Synthesis and Biological Activity of 7,8-Disubstituted Isoalloxazines. Synthesis of Nitrogen Mustard Derivatives
R. D. Faulkner and J. P. Lambooy
pp 292 - 294; DOI:
10.1021/jm00339a016
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Vitamin B6 Analogs. I. 5-Hydroxy-6-methyl-4-trifluoromethyl-3-pyridinemethanol Hydrochloride
Joseph L. Greene and John A. Montgomery
pp 294 - 297; DOI:
10.1021/jm00339a017
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Strophanthidin Cardenolides Containing Hexoses of the Mannose Series
W. Werner Zorbach, Seitaro Saeki, and Wolfgang Bühler
pp 298 - 301; DOI:
10.1021/jm00339a018
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New Synthesis and Structure Activity Relationship in the 17-Alkylated Progesterone Series
R. Deghenghi, C. Revesz, and R. Gaudry
pp 301 - 304; DOI:
10.1021/jm00339a019
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Some 3-Phenyl Derivatives of Pregnane-11,20-dione
Jean F. Pulis, B. G. Christensen, and L. H. Sarett
pp 304 - 306; DOI:
10.1021/jm00339a020
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Preparation and Anticonvulsant Activity of N-Substituted Benzenedisulfonamides
Gerald F. Holland, William H. Funderburk, and Kenneth F. Finger
pp 307 - 312; DOI:
10.1021/jm00339a021
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The Synthesis of Some Substituted m-Benzenedisulfonamides
John G. Topliss, Maria C. Daly, Anet Lipski, Elizabeth P. Shapiro, and Nathan Sperber
pp 312 - 315; DOI:
10.1021/jm00339a022
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The Synthesis and Pharmacological Action of Tremetone
Douglas M. Bowen, Joseph I. DeGraw, Vinod R. Shah, and William A. Bonner
pp 315 - 319; DOI:
10.1021/jm00339a023
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Electronic Effects of para-Substituents on the Local Anesthetic Activity of 2-Diethylaminoethyl Benzoate and Related Compounds1a,1b
Alvin M. Galinsky, James E. Gearien, Alfred J. Perkins, and Stanley V. Susina
pp 320 - 322; DOI:
10.1021/jm00339a024
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Structures Related to Morphine. XXV.1a 5-Propyl- and 5,9-Dipropyl-6,7-benzomorphans and a Pharmacologic Summary1b
J. Harrison Ager, S. E. Fullerton, and Everette L. May
pp 322 - 325; DOI:
10.1021/jm00339a025
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Stereochemistry of the Interaction of Enantiometic 1,3-Dioxolane Analogs of Muscarone with Cholinergic Receptors
B. Belleau and J. Puranen
pp 325 - 328; DOI:
10.1021/jm00339a026
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Esters of Some Steroidal 3β-Hydroxy-4,6-dienes and their Biological Activity
John S. Baran
pp 329 - 330; DOI:
10.1021/jm00339a027
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Synthesis of Some Steroidal [3,2-d]- and [17,16-d]-2′,6′- Diaminopyrimidines
Leland L. Smith, Daniel M. Teller, and Theodore Foell
pp 330 - 332; DOI:
10.1021/jm00339a028
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Hydroxypyrimidine-5-carboxaldehyde Derivatives in Cancer Chemotherapy
Richard H. Wiley, A. B. Canon, and Karl F. Hussung
pp 333 - 334; DOI:
10.1021/jm00339a029
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Orotylamino Acids
Donald G. Crosby and Robert V. Berthold
pp 334 - 335; DOI:
10.1021/jm00339a030
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1,4-Di(D-glycosyl)piperazine Derivatives as Oxyuricidal Agents
Tellis A. Martin, Paul S. Prickett, Allan G. Wheeler, and Howard R. Williams
pp 336 - 337; DOI:
10.1021/jm00339a031
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A Pharmacological Investigation of Potential Antidepressants of the Amitriptyline-Type
Jane Stewart, Marie-Paule Charest, and Ferenc Herr
pp 338 - 339; DOI:
10.1021/jm00339a032
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Book Reviews

pp 340 - 342; DOI:
10.1021/jm00339a034
PDF

Issue 4


Demethylation Studies. IV. The in vitro and in vivo Cleavage of Alkyl- and Arylalkyl-p-nitrophenyl Ethers
Robert E. McMahon, Hilman W. Culp, Jack Mills, and Frederick J. Marshall
pp 343 - 346; DOI:
10.1021/jm00340a001
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Esters of 4-{3-[2-(Trifluoromethyl)phenothiazin-10-yl]propyl}-1-piperazineëthanol as Long-Acting Tranquilizing Agents. Synthesis of 4-{3-[2-(Trifluoromethyl)- phenothiazin-10-yl]propyl}-1-piperazineëthanol-ethyl-C14 and its Ester with Heptanoic Acid. III
Harry L. Yale, Allen I. Cohen, and Francis Sowinski
pp 347 - 350; DOI:
10.1021/jm00340a002
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Substituted 2-Mercaptoisobutyramides and 2-Ethyl-2-mercaptobutyramides
H. Lehr, L. O. Randall, and M. W. Goldberg
pp 351 - 355; DOI:
10.1021/jm00340a003
PDF
Strong Analgesics: Some N-(Piperidinoalkyl)-anilides
P. M. Carabateas, W. F. Wetterau, and L. Grumbach
pp 355 - 357; DOI:
10.1021/jm00340a004
PDF
Investigations in Heterocycles. XIII. Structure-Activity Relationships of Heterocyclic Compounds with Potent Analgetic Effects
George DeStevens, Angela Halamandaris, Patricia Strachan, Ellen Donoghue, Louis Dorfman, and Charles F. Huebner
pp 357 - 361; DOI:
10.1021/jm00340a005
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An Empirical Relationship between Anthelmintic Activity and Chemical Structure
M. Harfenist
pp 361 - 363; DOI:
10.1021/jm00340a006
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The Synthesis of Δ11-17α-Acetoxyprogesterone and Related Compounds
John P. Dusza, J. P. Joseph, Milton Heller, and Seymour Bernstein
pp 364 - 369; DOI:
10.1021/jm00340a007
PDF
Anthelmintic Agents. 1,2-Dihydro-s-Triazines
Barbara Roth, Robert B. Burrows, and George H. Hitchings
pp 370 - 378; DOI:
10.1021/jm00340a008
PDF
The Synthesis and Pharmacological Activity of Some Chloro-α-alkyltryptamines
B. A. Whittle and E. H. P. Young
pp 378 - 380; DOI:
10.1021/jm00340a009
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Hypotensives. V. 2,2,6,6-Tetramethylpiperidines and Related Compounds
Jerry E. Robertson, John H. Biel, and Frank DiPierro
pp 381 - 384; DOI:
10.1021/jm00340a010
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Bicyclic Homologs of Piperazine. V.1,3 Synthesis and Analgesic Activity of 3-Methyl-3,8-diazabicyclooctane Derivatives
Giorgio Cignarella, Emilio Occelli, Giulio Maffii, and Emilio Testa
pp 385 - 387; DOI:
10.1021/jm00340a011
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Spiranes. III.1a,b Azaspiranes and Intermediates1c
Leonard M. Rice, Charles F. Geschickter, and Charles H. Grogan
pp 388 - 402; DOI:
10.1021/jm00340a012
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Cyclopropane Methonium Compounds
Alfred Burger and G. R. Bedford
pp 402 - 405; DOI:
10.1021/jm00340a013
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6-Deoxytetracyclines. V.1a 7,9-Disubstituted Products
John L. Spencer, Joseph J. Hlavka, Joseph Petisi, Helen M. Krazinski, and J. H. Boothe
pp 405 - 407; DOI:
10.1021/jm00340a014
PDF
Analogs of the Aminonucleoside Derived from Puromycin. The Synthesis of 3′-Amino-3′-deoxyguanosine and 3′-Amino-3′-deoxycrotonoside
Henry M. Kissman, Arlene Small Hoffman, and Martin J. Weiss
pp 407 - 409; DOI:
10.1021/jm00340a015
PDF
The Synthesis of Analogs of the Aminonucleoside from Puromycin1: 3′-Amino-3′-deoxyinosine and 2,3′-Diamino-3′-deoxyadenosine2
L. Goldman, J. W. Marsico, and M. J. Weiss
pp 410 - 413; DOI:
10.1021/jm00340a016
PDF
Synthesis and Reactions of 3′-Amino-3′-deoxyribosides of 6-Chloropurine
L. Goldman and J. W. Marsico
pp 413 - 423; DOI:
10.1021/jm00340a017
PDF
The Chemistry of Antimycin A. XI. N-Substituted 3-Formamidosalicylic Amides
J. P. Dickie, M. E. Loomans, T. M. Farley, and F. M. Strong
pp 424 - 427; DOI:
10.1021/jm00340a018
PDF
Iodination of 2′-Deoxycytidine and Related Substances
Pauline K. Chang and Arnold D. Welch
pp 428 - 430; DOI:
10.1021/jm00340a019
PDF
Studies on Methylglyoxal Bis(guanylhydrazone)1 Analogs. II. Structural Variations on Methylglyoxal Bis(guanylhydrazone)2
Fred Baiocchi, C. C. Cheng, W. J. Haggerty, Leland R. Lewis, T. K. Liao, Wayne H. Nyberg, Darrell E. O'Brien, and Eugene G. Podrebarac
pp 431 - 435; DOI:
10.1021/jm00340a020
PDF
Synthesis of Possible Cancer Chemotherapeutic Compounds Based on Enzyme Approach. IV. Aziridine Derivatives
K. C. Tsou, K. Hoegerle, and Helen C. F. Su
pp 435 - 439; DOI:
10.1021/jm00340a021
PDF
Synthesis of N,N-Bis(2-chloroethyl)-DL-phenylalanine Hydrochloride
William W. Lee, George L. Tong, Abelardo P. Martinez, Boris Weinstein, Marc G. M. Schelstraete, B. R. Baker, and Leon Goodman
pp 439 - 442; DOI:
10.1021/jm00340a022
PDF
Synthesis of β-Phenylserines
S. Wawzonek and W. G. Gaffield
pp 442 - 444; DOI:
10.1021/jm00340a023
PDF
Synthetic Schistosomicides. III. 5-(4-Amino-1-naphthylazo)uracil and Related Heterocyclic Azo Compounds
Edward F. Elslager and Donald F. Worth
pp 444 - 447; DOI:
10.1021/jm00340a024
PDF
Subsidiary Constituents from Amanita Muscaria
A. V. Subbaratnam and William B. Cook
pp 448 - 449; DOI:
10.1021/jm00340a025
PDF
Potential Carcinolytic Agents. I. Derivatives of P,P-Bis(1-aziridinyl)phosphinic Amide
Orrie M. Friedman, Robert S. Levi, Zinon B. Papanastassiou, and Wilson M. Whaley
pp 449 - 450; DOI:
10.1021/jm00340a026
PDF
Thiopegan Derivatives. XXIII. Synthesis of 5H-Thiazolo[3,2-a]quinazolin-5-one and 5H-Thiazolo[2,3-b]quinazolin-5-one Derivatives Containing Phenolic, Alkoxy, and Alkyl Groups
K. S. Dhami, S. S. Arora, and K. S. Narang
pp 450 - 452; DOI:
10.1021/jm00340a027
PDF
The Synthesis of Halogenated Tuberculostatic Thiocarbanilides
D. Q. Cuong, N. P. Buu-Hoï, and N. D. Xuong
pp 452 - 455; DOI:
10.1021/jm00340a028
PDF
Quaternary Ammonium Compounds. IV. Antiacetylcholinesterase Activity and Ring Size in Aromatic Quaternary Ammonium Compounds
J. Thomas
pp 456 - 457; DOI:
10.1021/jm00340a029
PDF
Esters of Farnesylacetic Acid
Cesare Cardani, Bruno Cavalleri, and Enrico Adami
pp 457 - 458; DOI:
10.1021/jm00340a030
PDF
Chemical Models of Drug-Receptor Interaction. II
Alexander Gero
pp 458 - 459; DOI:
10.1021/jm00340a031
PDF
Thyroxine Analogs. X.1 3,5-Diamino-, 3,5-Dicyano-, and 3,5-Dicarboxy-DL-thyronines
Eugene C. Jorgensen and Robert A. Wiley
pp 459 - 462; DOI:
10.1021/jm00340a032
PDF
1-(β-Chloroethyl)-3-carbamylpyridinium Chloride. Prototype of a New Class of Latently Cytotoxic Potential Antitumor Agents
Orrie M. Friedman, Kurt Pollak, and Ezra Khedouri
pp 462 - 463; DOI:
10.1021/jm00340a033
PDF
Gentamicin,1 a New Antibiotic Complex from Micromonospora
Marvin J. Weinstein, George M. Luedemann, Edwin M. Oden, Gerald H. Wagman, Jean Pierre Rosselet, Joseph A. Marquez, Carmine T. Coniglio, William Charney, Hershel L. Herzog, and Jack Black
pp 463 - 464; DOI:
10.1021/jm00340a034
PDF
Effects of d,l-3-Phthalimidoglutarimide and N-Phthalyl-d,l-aspartimide on Rat Pregnancy
D. Misiti, V. Rosnath, G. Bignami, F. Bovet-Nitti, and D. Bovet
pp 464 - 465; DOI:
10.1021/jm00340a035
PDF
Book Reviews

pp 466 - 466; DOI:
10.1021/jm00340a036
PDF

Issue 5


Pyrimidines. XI. Structural Variations of 2,4-Diamino-6-(halogenoanilino)-5-nitrosopyrimidines
Darrell E. O'Brien, Fred Baiocchi, Roland K. Robins, and C. C. Cheng
pp 467 - 471; DOI:
10.1021/jm00341a001
PDF
Synthesis and Antitumor Activity of 9-(Tetrahydro-2-furyl)purine Analogs of Biologically Important Deoxynucleosides
William A. Bowles, F. Howard Schneider, Leland R. Lewis, and Roland K. Robins
pp 471 - 480; DOI:
10.1021/jm00341a002
PDF
The Biological and Physical Properties of the Azaindoles
Terrine K. Adler and Adrien Albert
pp 480 - 483; DOI:
10.1021/jm00341a003
PDF
Dihydro-1,3-oxazine Derivatives and their Antitumor Activity
J. B. Chylińska, T. Urbański, and M. Mordarski
pp 484 - 487; DOI:
10.1021/jm00341a004
PDF
The Physical Chemical Characterization of the Products, Equilibria, and Kinetics of the Complex Transformations of the Antibiotic Porfiromycin
Edward R. Garrett
pp 488 - 501; DOI:
10.1021/jm00341a005
PDF
The Preparation and Bacteriostatic Activity of Halogenated Carbanilates
David J. Beaver, Daniel P. Roman, and Paul J. Stoffel
pp 501 - 506; DOI:
10.1021/jm00341a006
PDF
The Synthesis of Some New Sulfonylureas
Bernard Loev, Kenneth M. Snader, and Donald T. Walz
pp 506 - 508; DOI:
10.1021/jm00341a007
PDF
Antiradiation Compounds. IV. Trithiocarbonates of β-Mercaptoethylguanidines
William O. Foye, James Mickles, Ronald N. Duvall, and James R. Marshall
pp 509 - 512; DOI:
10.1021/jm00341a008
PDF
New Psychotropic Agents. VI.1 Basic Esters of 5-Hydroxydibenzo[a,d]cycloheptadiene-5-carboxylic Acid
M. A. Davis, F. A. Sunahara, F. Herr, and R. Gaudry
pp 513 - 516; DOI:
10.1021/jm00341a009
PDF
Some Reactions and Derivatives of 2,2-Diphenylcyclopentanone
Stuart S. Kulp, Velmer B. Fish, and Nelson R. Easton
pp 516 - 519; DOI:
10.1021/jm00341a010
PDF
Anorexigenic Agents: Aromatic Substituted 1-Phenyl-2-propylamines
Gerald F. Holland, Carl J. Buck, and Albert Weissman
pp 519 - 524; DOI:
10.1021/jm00341a011
PDF
The Synthesis of 8-D-Phenylalanine-, 8-p-Fluoro-L-phenylalanine-, and 8-p-Fluoro-D-phenylalanine-bradykinin
E. D. Nicolaides, M. K. Craft, and H. A. DeWald
pp 524 - 528; DOI:
10.1021/jm00341a012
PDF
The Anticonvulsant Properties of Some Substituted Benzamides
Bruce W. Horrom and T. E. Lynes
pp 528 - 532; DOI:
10.1021/jm00341a013
PDF
2,2,3-Triarylpropionitriles and Related Compounds as Hypocholesterolemic Agents
Mel Perelman and Steve Mizsak
pp 533 - 538; DOI:
10.1021/jm00341a014
PDF
Centrally Active 2-(Substituted phenyl)-γ-aminobutyric Acids
F. Leonard, A. Wajngurt, M. Klein, and H. Meyer
pp 539 - 541; DOI:
10.1021/jm00341a015
PDF
Synthesis and Pharmacological Study of New Piperazine Derivatives. I. Benzylpiperazines
J. R. Boissier, R. Ratouis, and C. Dumont
pp 541 - 544; DOI:
10.1021/jm00341a016
PDF
Substituted 2,3-Dihydro-1,5-benzothiazepin-4(5H)-ones and 3,4-Dihydro-2-phenyl-(2H)-1,6-benzothiazocin-5(6H)-ones
John Krapcho, Ervin R. Spitzmiller, and Chester F. Turk
pp 544 - 546; DOI:
10.1021/jm00341a017
PDF
Analgesics. Basic Amides of α-Alkoxydiphenylacetic Acids
John Krapcho and Chester F. Turk
pp 547 - 550; DOI:
10.1021/jm00341a018
PDF
Synthesis of 5-Substituted Pyrimidines
T. V. Rajkumar and Stephen B. Binkley
pp 550 - 554; DOI:
10.1021/jm00341a019
PDF
Thyromimetics. I. The Synthesis and Hypocholesteremic Activity of Some 3′ and 3′,5′-Alkyl and Aryl-3,5-diiodothyronines
Benjamin Blank, Francis R. Pfeiffer, Cyrus M. Greenberg, and James F. Kerwin
pp 554 - 560; DOI:
10.1021/jm00341a020
PDF
Thyromimetics. II. The Synthesis and Hypocholesteremic Activity of Some β-Diethylaminoethyl Esters of Iodinated Thyroalkanoic Acids
Benjamin Blank, Francis R. Pfeiffer, Cyrus M. Greenberg, and James F. Kerwin
pp 560 - 563; DOI:
10.1021/jm00341a021
PDF
Synthesis, Properties, and Enzymatic Reactions of Some Aminoacyladenines
John J. Brink and Arnold H. Schein
pp 563 - 566; DOI:
10.1021/jm00341a022
PDF
Synthesis of Mustards from Putrescine, Cadaverine, and 1,3-Diaminopropane
William W. Lee, Bernard J. Berridge, Leonard O. Ross, and Leon Goodman
pp 567 - 569; DOI:
10.1021/jm00341a023
PDF
Transformation of Codeine to an Analog of the Potent Analgesic Phenazocine
Lewis J. Sargent and J. Harrison Ager
pp 569 - 572; DOI:
10.1021/jm00341a024
PDF
Antibacterial Agents. Some New Halomethyl Aryl Ketones
G. Cavallini, E. Massarani, D. Nardi, L. Mauri, F. Tenconi, F. Pacchiano, and P. Mantegazza
pp 573 - 578; DOI:
10.1021/jm00341a025
PDF
Conformation of N-(β-Chloroethyl)-2-phenoxyethylamines in Relation to Adrenergic Blocking Activity
B. Belleau and P. Cooper
pp 579 - 583; DOI:
10.1021/jm00341a026
PDF
Synthesis and Pharmacological Properties of Phenyl-Substituted Biurets
J. D. McColl, F. L. Chubb, C. F. Lee, A. Hajdu, and J. Komlossy
pp 584 - 587; DOI:
10.1021/jm00341a027
PDF
Bacteriostats. VI.1a Bacteriostatic Activities of Some Substituted Guanidines1b
A. F. McKay, D. L. Garmaise, H. A. Baker, L. R. Hawkins, V. Falta, R. Gaudry, and G. Y. Paris
pp 587 - 595; DOI:
10.1021/jm00341a028
PDF
The Hypotensive Activity of N-Cyclohexyl and N-Methyl Derivatives of Alkylenediamines
James H. Short, William L. Chan, Morris Freifelder, Douglas G. Mikolasek, John L. Schmidt, Hollis G. Schoepke, Charles Shannon, and George R. Stone
pp 596 - 598; DOI:
10.1021/jm00341a029
PDF
Synthesis of Oncolytic Analogs of 1,2-Dimethyl-4,5-diaminobenzene
D. W. Woolley and John Morrow Stewart
pp 599 - 601; DOI:
10.1021/jm00341a030
PDF
Substituted 2-Aminobenzimidazoles
Lionel Joseph
pp 601 - 601; DOI:
10.1021/jm00341a031
PDF
5-Allyluridine
Harry J. Minnemeyer, Howard Tieckelmann, and James F. Holland
pp 602 - 603; DOI:
10.1021/jm00341a032
PDF
6-Ethyl-1,2,4,2H-thiadiazine-3,5(4H,6H)dione 1,1-Dioxide
S. Wawzonek and R. L. Abbott
pp 603 - 604; DOI:
10.1021/jm00341a033
PDF
Derivatives of 1-Phenyl-4-(2-hydroxy-3-methoxypropyl)piperazine
Hilda Howell, C. B. Pollard, Lemont B. Kier, and Harry H. Sisler
pp 604 - 607; DOI:
10.1021/jm00341a034
PDF
The Synthesis of Two New Metabolites of Catecholamines: 3,4-Dihydroxyphenylethyleneglycol and 4-Hydroxy-3-methoxyphenylethyleneglycol
J. D. Benigni and Anthony J. Verbiscar
pp 607 - 608; DOI:
10.1021/jm00341a035
PDF
The Synthesis of 15β-Fluoro Corticoids
Donald E. Ayer
pp 608 - 610; DOI:
10.1021/jm00341a036
PDF
Steroid Dimethylhydrazones
Richard H. Wiley and Sae Hee Chang
pp 610 - 611; DOI:
10.1021/jm00341a037
PDF
The Microbiolgoical Preparation of 17-Deoxytriamcinolone
Chester E. Holmlund, Louis I. Feldman, Neil E. Rigler, Ralph H. Evans, Robert H. Blank, and Barbara E. Nielson
pp 611 - 613; DOI:
10.1021/jm00341a038
PDF
Peptinogan, a Polypeptide Moiety of Actinogan with Antitumor Properties
H. Schmitz, R. L. DeVault, and I. R. Hooper
pp 613 - 613; DOI:
10.1021/jm00341a039
PDF
2-Benzyl- and 2-Phenyl-3,4-dihydroxyphenyl-alanine
Alfred Burger, William E. Coyne, and Gerard Janssen
pp 614 - 616; DOI:
10.1021/jm00341a040
PDF
The Tumor-Enhancing and Irritant Principles from Croton tiglium L.
B. L. Van Duuren, E. Arroyo, and L. Orris
pp 616 - 617; DOI:
10.1021/jm00341a041
PDF
Aldosterone Antagonists. 2′3′α-Tetrahydrofuran-2′-spiro-17-(4-androsten-3-one) and Related Compounds
G. E. Arth, Harvey Schwam, L. H. Sarett, and M. Glitzer
pp 617 - 618; DOI:
10.1021/jm00341a042
PDF
Thymine Analogs: The Synthesis of 5-Difluoromethyluracil
Mathias P. Mertes and Souheil E. Saheb
pp 619 - 619; DOI:
10.1021/jm00341a043
PDF
Book Reviews

pp 619 - 620; DOI:
10.1021/jm00341a044
PDF

Issue 6


Metabolism of Tranylcypromine-C14 and dl-Amphetamine-C14 in the Rat
John J. Alleva
pp 621 - 624; DOI:
10.1021/jm00342a001
PDF
Kinetics of the Formalin Inactivation of Poliovirus
Martin L. Black and Eugene A. Timm
pp 624 - 627; DOI:
10.1021/jm00342a002
PDF
A Quinoline N-Oxide Analog of Chloramphenicol
John R. E. Hoover and Benjamin Blank
pp 628 - 632; DOI:
10.1021/jm00342a003
PDF
Chemotherapeutic Nitrofurans. IX.1 2-[1-Acyl-2-(5-nitrofurfurylidene)hydrazino]acetamides
Frank F. Ebetino, Warren F. Carey, and Benjamin F. Stevenson
pp 633 - 637; DOI:
10.1021/jm00342a004
PDF
N-Mono- and N,N-Dialkyl-N′-1-naphthylalkylenediamines
Leslie M. Werbel, David B. Capps, Edward F. Elslager, William Pearlman, Franklin W. Short, Enta A. Weinstein, and Donald F. Worth
pp 637 - 646; DOI:
10.1021/jm00342a005
PDF
Synthetic Schistosomicides. IV. 5-[4-(2-Diethylamino-ethylamino)-1-naphthylazo]uracil and Related [4-(Aminoalkylamino)-1-naphthylazo]heterocyclic Compounds
Edward F. Elslager, David B. Capps, Dianne H. Kurtz, Leslie M. Werbel, and Donald F. Worth
pp 646 - 653; DOI:
10.1021/jm00342a006
PDF
Preparation and Antibiotic Properties of Some Phosphinylaminopenicillanic Acids and Phosphinothioylaminopenicillanic Acids
B. K. Koe, T. A. Seto, A. R. English, and T. J. McBride
pp 653 - 658; DOI:
10.1021/jm00342a007
PDF
Analogs of Tetrahydrofolic Acid. VIII.1,2 Synthesis of N-[1-(2-Amino-4-mercapto-6-methyl-5-pyrimidyl)-3-propyl]-p- aminobenzoyl-L-glutamic Acid, a Mercapto Analog
B. R. Baker, C. E. Morreal, and Beng-Thong Ho
pp 658 - 664; DOI:
10.1021/jm00342a008
PDF
Analogs of Tetrahydrofolic Acid. IX.1,2 Synthesis of N-[1-(2-Amino-4-hydroxy-6-phenyl-5-pyrimidyl)-3-propyl]-p- aminobenzoyl-L-glutamic Acid, a “Nonclassical” Inhibitor of Some Folic Cofactor Area Enzymes
B. R. Baker and Howard S. Shapiro
pp 664 - 669; DOI:
10.1021/jm00342a009
PDF
The Synthesis of Antineoplastic Agents. XXXII. N-Nitrosoureas.1 I.
Thomas P. Johnston, George S. McCaleb, and John A. Montgomery
pp 669 - 681; DOI:
10.1021/jm00342a010
PDF
Hexahydropyrimidines. III.1 A Study of 2-Substituted 1,3-Bis(p-methoxybenzyl)hexahydropyrimidines and 2-Substituted 1,3-Bis(p-chlorobenzyl)hexahydropyrimidines as Transport Molecules for Tumor Inhibition2
John H. Billman and John L. Meisenheimer
pp 682 - 683; DOI:
10.1021/jm00342a011
PDF
2′-Deoxythioguanosine and Related Nucleosides
Robert H. Iwamoto, Edward M. Acton, and Leon Goodman
pp 684 - 688; DOI:
10.1021/jm00342a012
PDF
Pyrimidines. I. The Synthesis of 6-Fluorocytosine and Related Compounds
Iris Wempen and Jack J. Fox
pp 688 - 693; DOI:
10.1021/jm00342a013
PDF
Synthesis of Possible Cancer Chemotherapeutic Compounds Based on Enzyme Approach. V. Tetrazolium Nitrogen Mustards
K. C. Tsou and Helen C. F. Su
pp 693 - 696; DOI:
10.1021/jm00342a014
PDF
Nucleosides. XVII. Pyrimidinyl Amino Acids
Tohru Ueda and Jack J. Fox
pp 697 - 701; DOI:
10.1021/jm00342a015
PDF
Imidazolidines. III.1a 2-Substituted 1,3-Bis-(o-hydroxybenzyl)-imidazolidines1b
John H. Billman and Linneaus C. Dorman
pp 701 - 705; DOI:
10.1021/jm00342a016
PDF
Potential Antihypertensive Agents. Some Guanidine Derivatives
D. I. Barron, P. M. G. Bavin, G. J. Durant, I. L. Natoff, R. G. W. Spickett, and D. K. Vallance
pp 705 - 711; DOI:
10.1021/jm00342a017
PDF
Benzo[b]thiophene Derivatives. IV.1 The Preparation and Pharmacological Activity of Compounds Related to Serotonin and Gramine
J. J. Lewis, M. Martin-Smith, T. C. Muir, S. N. Nanjappa, and S. T. Reid
pp 711 - 716; DOI:
10.1021/jm00342a018
PDF
Synthesis and Pharmacological Activity of Fluorinated Tryptamine Derivatives
Asher Kalir and Stephen Szara
pp 716 - 719; DOI:
10.1021/jm00342a019
PDF
Acyltryptamines. II. Synthesis of Acyltryptamines, Indazoles, and Azepinoindoles from the Acylphenylhydrazones of 2,3-Piperidinedione
Maximilian von Strandtmann, Marvin P. Cohen, and John Shavel
pp 719 - 725; DOI:
10.1021/jm00342a020
PDF
C-19-Functional Steroids. VI.1,2 Testosterone Derivatives3
Manfred E. Wolff and Timothy Jen
pp 726 - 732; DOI:
10.1021/jm00342a021
PDF
Steroidal Aldosterone Blockers. VII
Edward A. Brown and Robert R. Burtner
pp 732 - 735; DOI:
10.1021/jm00342a022
PDF
Anabolic Agents. 2-Methylene-5α-androstane Derivatives
R. E. Counsell and P. D. Klimstra
pp 736 - 738; DOI:
10.1021/jm00342a023
PDF
The Synthesis of 1-Lysine, 1-Ornithine, 1-Citrulline, 1-Glutamic Acid, and 1-Desarginine Bradykinin
E. D. Nicolaides, H. A. DeWald, and M. K. Craft
pp 739 - 741; DOI:
10.1021/jm00342a024
PDF
The Synthesis of 6-O-Carbamyl-L-Serine, 6-D-Serine, and 6-L-Threonine Bradykinin
H. A. DeWald, M. K. Craft, and E. D. Nicolaides
pp 741 - 745; DOI:
10.1021/jm00342a025
PDF
Synthesis and Antibacterial Properties of Some Tripeptides
S. Shankman, S. Higa, S. Makineni, and W. Noll
pp 746 - 751; DOI:
10.1021/jm00342a026
PDF
A New Series of Substances which Block the Adrenergic β-Receptors
H. Corrodi, H. Persson, A. Carlsson, and J. Roberts
pp 751 - 755; DOI:
10.1021/jm00342a027
PDF
Occupancy of Adrenergic Receptors and Inhibition of Catechol O-Methyl Transferase by Tropolones
B. Belleau and J. Burba
pp 755 - 759; DOI:
10.1021/jm00342a028
PDF
The Adamantyl Group in Medicinal Agents. I. Hypoglycemic N-Arylsulfonyl-N′-adamantylureas
Koert Gerzon, Eriks V. Krumkalns, Richard L. Brindle, Frederick J. Marshall, and Mary A. Root
pp 760 - 763; DOI:
10.1021/jm00342a029
PDF
Bicyclic Homologs of Piperazine. VI.1 Synthesis and Analgesic Activity of 3-Substituted 8-Propionyl-3,8-diazabicyclo[3.2.1]octanes
Giorgio Cignarella, Emilio Occelli, Gianfranco Cristiani, Lilia Paduano, and Emilio Testa
pp 764 - 766; DOI:
10.1021/jm00342a030
PDF
Dibenzo[b,e][1,4]diazepines
A. R. Hanze, R. E. Strube, and M. E. Greig
pp 767 - 771; DOI:
10.1021/jm00342a031
PDF
Dihydroazepinone Chemistry. IV. 1-Aminoalkyl-1,3-dihydro-3,5,7-trimethyl-2H-azepin-2-ones
Leo A. Paquette and Jack K. Reed
pp 771 - 774; DOI:
10.1021/jm00342a032
PDF
Synthesis of Unsymmetrical Diphenylalkenes
Jean-François Miquel, Hans Wåhlstam, Knut Olsson, and Bertil Sundbeck
pp 774 - 780; DOI:
10.1021/jm00342a033
PDF
Synthesis and Antibacterial Activity of Symmetrical Bis-quaternaries Derived from β-Ionone and Related Compounds
S. Teitel, P. Heck, E. Grunberg, and M. W. Goldberg
pp 780 - 787; DOI:
10.1021/jm00342a034
PDF
Antiviral Activity of Glyoxals and Derivatives
Elvin L. Anderson, John E. Casey, Morton Emas, Elizabeth E. Force, Erling M. Jensen, Ralph S. Matz, and Donald E. Rivard
pp 787 - 791; DOI:
10.1021/jm00342a035
PDF
Steroid Homolog Containing a Pyrazole Nucleus
Julius A. Vida and Marcel Gut
pp 792 - 793; DOI:
10.1021/jm00342a036
PDF
Steroidal [17,16-c]Pyrazoles
C. H. Robinson, N. F. Bruce, and E. P. Oliveto
pp 793 - 795; DOI:
10.1021/jm00342a037
PDF
Anesthetic Steroid Derivatives
H. D. Brown and L. H. Sarett
pp 795 - 796; DOI:
10.1021/jm00342a038
PDF
π-Complexes with Biologically Significant Materials. II.1 Acetylergosterol Iron Tricarbonyl
A. Nakamura and M. Tsutsui
pp 796 - 798; DOI:
10.1021/jm00342a039
PDF
Synthesis of 16-Chlorinated Pregnenes
Susumu Nakanishi
pp 798 - 799; DOI:
10.1021/jm00342a040
PDF
Synthesis1 of Ring-Labeled L-Thyroxine-C14
Melvin J. Gortatowski, Lindy F. Kumagai, and Charles D. West
pp 800 - 802; DOI:
10.1021/jm00342a041
PDF
Bicyclic Imides and Isoindolines
Charles H. Grogan and Leonard M. Rice
pp 802 - 805; DOI:
10.1021/jm00342a042
PDF
Hypotensives. VI.1 Disubstituted Alkylenediamines and Related Compounds
Jerry E. Robertson, John H. Biel, Thomas F. Mitchell, Wallace K. Hoya, and Helen A. Leiser
pp 805 - 807; DOI:
10.1021/jm00342a043
PDF
3,6-Disubstituted Pyridazines
Douglas I. Relyea, J. A. Riddell, and Pliny O. Tawney
pp 807 - 809; DOI:
10.1021/jm00342a044
PDF
Nitrogen Substituted Phenoxazines
Andrew E. Gal and Souren Avakian
pp 809 - 811; DOI:
10.1021/jm00342a045
PDF
The Effect of Piperidinecarboxamide Derivatives on Isolated Human Plasma Cholinesterase
A. Lasslo, J. G. Beasley, G. G. Nelms, and G. J. Epperson
pp 811 - 813; DOI:
10.1021/jm00342a046
PDF
N-Alicyclic Amphetamines
Morris Freifelder
pp 813 - 813; DOI:
10.1021/jm00342a047
PDF
Antispasmodics. II.1 α-Phenyl-α-substituted 2-Pyridinebutanols and Related Compounds
John Krapcho
pp 814 - 815; DOI:
10.1021/jm00342a048
PDF
Bacteriostats. VII. Substituted Benzylphenols
A. F. McKay, H. A. Baker, R. Gaudry, D. L. Garmaise, and R. J. Ranz
pp 816 - 817; DOI:
10.1021/jm00342a049
PDF
Some 2-Substituted Aminopurines and Purine Analogs
R. M. Cresswell, T. Strauss, and George Bosworth Brown
pp 817 - 819; DOI:
10.1021/jm00342a050
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Hydroxymethylglyoxal Bisguanylhydrazone
Ti Li Loo, Robert L. Dion, Jack D. Davidson, and Richard H. Adamson
pp 819 - 820; DOI:
10.1021/jm00342a051
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4-(1-Carboxyethyl)-1,4-oxathianium Bromide
Carl Tabb Bahner and Gordon Senter
pp 820 - 820; DOI:
10.1021/jm00342a052
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Some Esters of dl-exo-3-Dimethylaminoisoborneol
Edgar A. Steck and Stephen T. Ross
pp 820 - 821; DOI:
10.1021/jm00342a053
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Aromatic Azo Acids as Possible Antineoplastic Compounds
Norman Rabjohn and J. F. Porter
pp 821 - 822; DOI:
10.1021/jm00342a054
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Some Derivatives of 2,2′-(Phenylimino)diethanol
Alex Cohen and R. Stuart Tipson
pp 822 - 824; DOI:
10.1021/jm00342a055
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Synthesis of a 6-Mercaptopurine N-Oxide
Gershon Levin and George Bosworth Brown
pp 825 - 825; DOI:
10.1021/jm00342a056
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Experimental Chemotherapy.
Alfred Burger
pp 825 - 826; DOI:
10.1021/jm00342a057
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Enzyme and Metabolic Inhibitors. Vol. 1. General Principles of Inhibition.
R. Bruce Martin
pp 826 - 826; DOI:
10.1021/jm00342a058
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Spectrometric Identification of Organic Compounds.
O. R. Rodig
pp 826 - 827; DOI:
10.1021/jm00342a059
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Keeping up with Pharmacology.
Alfred Burger
pp 827 - 827; DOI:
10.1021/jm00342a060
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Progress in Medicinal Chemistry.
Alfred Burger
pp 827 - 827; DOI:
10.1021/jm00342a061
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Progress in Drug Research.
Alfred Burger
pp 828 - 828; DOI:
10.1021/jm00342a062
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Grundlagen der Arzneimittelforschung und der synthetischen Arzneimittel.
Alfred Burger
pp 828 - 828; DOI:
10.1021/jm00342a063
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Entstehung, Wachstum und Chemotherapie maligner Tumoren.
Alfred Burger
pp 828 - 828; DOI:
10.1021/jm00342a064
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Metabolic Inhibitors. A Comprehensive Treatise.
Alfred Burger
pp 828 - 829; DOI:
10.1021/jm00342a065
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Medicinal Chemistry.
Alfred Burger
pp 829 - 829; DOI:
10.1021/jm00342a066
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Additions and Corrections - The Pharmacology of a Series of Substituted 2-Halogenoalkylamines
J. D. P. Graham, and G. W. L. James
pp 829 - 829; DOI:
10.1021/jm00342a067
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Additions and Corrections - Synthesis of Derivatives of Isophthalmic Acid as X-Ray Contrast Agents
G. Brooke Hoey, Robert R. Rands, George DeLaMater, Douglas W. Chapman, and Philip E. Wiegert
pp 829 - 829; DOI:
10.1021/jm00342a068
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Additions and Corrections - Cyclopropyl and Cyclobutyl Analogs of Phenyl-Substituted Medicinal Agents
Alfred Burger, Robert T. Standridge, and E. J .Ariens
pp 829 - 829; DOI:
10.1021/jm00342a600
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Additions and Corrections - Synthesis and Reactions of 3'-Amino-3'-deoxyribosides of 6-Chloropurine
L. Goldman, and J. W. Marsico
pp 829 - 829; DOI:
10.1021/jm00342a601
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